Description

4-(4-Acetylphenyl)-3-Fluorobenzoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials, where its unique acetyl and fluorine substituents enable precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological or physical properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances bioavailability and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic display and lighting materials.
• Polymer Modification: Employed to introduce functional benzoic acid groups into polymer chains for specialty coatings and adhesives.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorinated compound libraries and reaction pathways.
• Coordination Chemistry: Acts as a ligand or precursor for metal-organic frameworks (MOFs) and catalysts.

Basic Information

Item	Detail
Product Name	4-(4-Acetylphenyl)-3-Fluorobenzoic Acid
CAS No.	1262005-90-2
Molecular Formula	C15H11FO3
Molecular Weight	258.25 g/mol
Synonyms	3-Fluoro-4'-(acetyl)benzoic Acid; 4'-Acetyl-3-fluorobiphenyl-4-carboxylic Acid; 3-Fluoro-4-(4-acetylphenyl)benzoic Acid; [1,1'-Biphenyl]-4-carboxylic Acid, 4'-acetyl-3-fluoro-; 4-(4-Acetylphenyl)-3-fluorobenzoic Acid; 4'-Acetyl-3-fluoro[1,1'-biphenyl]-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 4-(4-Acetylphenyl)-3-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.