Description

3-(4-Carboxy-3-Fluorophenyl)-4-Fluorobenzoic Acid is a high-purity, multi-functional aromatic carboxylic acid derivative, distinguished by its strategically placed fluorine atoms and carboxyl groups. This compound matters as a critical advanced pharmaceutical intermediate and a versatile building block for synthesizing complex organic molecules. It is primarily needed by R&D chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluorinated aromatic core.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers and polymers used in electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce carboxylic acid groups and fluorine into polymer backbones, enhancing material properties.
• Metal-Organic Framework (MOF) Synthesis: Employed as a multi-dentate organic linker for constructing porous coordination polymers with specific adsorption properties.
• Chemical Research & Development: A valuable reagent for academic and industrial research in medicinal chemistry, materials science, and synthetic methodology development.

Basic Information

Product Name	3-(4-Carboxy-3-Fluorophenyl)-4-Fluorobenzoic Acid
CAS No.	1262001-65-9
Molecular Formula	C14H8F2O4
Molecular Weight	278.21 g/mol
Synonyms	4,4'-Difluoro-3,3'-dicarboxybiphenyl; 3,3'-Biphenyldicarboxylic acid, 4,4'-difluoro-; 4-Fluoro-3-(4-fluoro-3-carboxyphenyl)benzoic acid; 4,4'-Difluoro-[1,1'-biphenyl]-3,3'-dicarboxylic acid; Biphenyl-3,3'-dicarboxylic acid, 4,4'-difluoro-; 1262001-65-9; 4,4'-Difluorobiphenyl-3,3'-dicarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Carboxy-3-Fluorophenyl)-4-Fluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency, suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases, oxidizing agents, and incompatible materials. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.