Description

3-(3-Acetylphenyl)-5-Fluorobenzoic Acid CAS NO 1261996-91-1 is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular architecture, which combines a fluorinated aromatic system with an acetylphenyl moiety, making it a versatile building block for targeted drug synthesis. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drugs, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing advanced herbicides and pesticides, where the fluorine atom can improve lipophilicity and biological activity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers with specific optical or electronic properties.
• Ligand Synthesis: Employed in organic and medicinal chemistry for constructing complex ligands used in catalysis or biochemical probes.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-(3-Acetylphenyl)-5-Fluorobenzoic Acid
CAS No.	1261996-91-1
Molecular Formula	C15H11FO3
Molecular Weight	258.25 g/mol
Synonyms	5-Fluoro-3'-(acetyl)benzoic Acid; 3'-Acetyl-5-fluorobiphenyl-3-carboxylic Acid; 3-(3-Acetylphenyl)-5-fluorobenzoic Acid; [1,1'-Biphenyl]-3-carboxylic Acid, 3'-acetyl-5-fluoro-; 5-Fluoro-3'-(acetyl)-[1,1'-biphenyl]-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-(3-Acetylphenyl)-5-Fluorobenzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.