Description

3-Fluoro-4-(4-Methylphenyl)Benzoic Acid is a high-purity fluorinated aromatic carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique structure, featuring both fluorine and a biaryl system, makes it essential for modulating the physicochemical properties and biological activity of target molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, anti-inflammatory agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, where the fluorine atom enhances metabolic stability and bioavailability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials in display technologies and organic light-emitting diodes.
• Polymer Modification: Incorporated as a monomer or additive to impart specific thermal, optical, or surface properties to high-performance polymers.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Probe Synthesis: Used in the creation of biochemical probes and diagnostic agents for imaging and assay development.

Basic Information

Item	Details
Product Name	3-Fluoro-4-(4-Methylphenyl)Benzoic Acid
CAS No.	1261953-35-8
Molecular Formula	C14H11FO2
Molecular Weight	230.24 g/mol
Synonyms	3-Fluoro-4-(p-tolyl)benzoic acid; 4'-Methyl-[1,1'-biphenyl]-3-carboxylic acid, 4-fluoro-; 4-Fluoro-4'-methylbiphenyl-3-carboxylic acid; 3-Fluoro-4-(4-methylphenyl)benzoic acid; 3-Fluoro-4-(p-methylphenyl)benzoic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-4'-methyl-; 1261953-35-8
EINECS	Contact for details

Quality Control

Our production of 3-Fluoro-4-(4-Methylphenyl)Benzoic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is characterized and released with a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to verify specifications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.