Description

3-(3-Methylphenyl)-5-Trifluoromethylbenzoic Acid is a high-value fluorinated aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the trifluoromethyl group, which imparts unique electronic and lipophilic properties to target molecules, enhancing their metabolic stability and bioavailability. This compound is primarily needed by pharmaceutical R&D and agrochemical manufacturers for the synthesis of novel active ingredients, as well as by specialty chemical producers developing advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves compound efficacy and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved thermal stability and electro-optical performance.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing material properties such as chemical resistance, weatherability, and surface characteristics.
• Organic Synthesis & Catalysis: A versatile reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis for constructing complex molecular architectures.
• Chemical Research (R&D): Fundamental research compound in academic and industrial laboratories exploring new fluorination methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	3-(3-Methylphenyl)-5-Trifluoromethylbenzoic Acid
CAS No.	1261953-10-9
Molecular Formula	C15H11F3O2
Molecular Weight	280.24 g/mol
Synonyms	5-(Trifluoromethyl)-[1,1'-biphenyl]-3-carboxylic acid, 3'-Methyl-; 3'-Methyl-5-(trifluoromethyl)[1,1'-biphenyl]-3-carboxylic Acid; 3-(3-Methylphenyl)-5-(trifluoromethyl)benzoic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 3'-methyl-5-(trifluoromethyl)-; 3-(m-Tolyl)-5-(trifluoromethyl)benzoic Acid; m-Tolyl-trifluoromethylbenzoic Acid
EINECS	Contact for details

Quality Control

Our 3-(3-Methylphenyl)-5-Trifluoromethylbenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with exacting industry standards. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production facilities and processes are designed to meet the stringent requirements of cGMP for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from strong bases, strong oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.