Description

[1,1'-Biphenyl]-4-Carboxylic Acid, 2,2',4'-Trifluoro- is a high-purity, fluorinated biphenyl carboxylic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring a fluorinated biphenyl core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides, where the trifluoro substitution pattern can influence biological activity.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for advanced display technologies.
• Organic Electronic Materials: Employed in the synthesis of monomers and polymers for organic light-emitting diodes (OLEDs) and other electronic applications.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct more complex biaryl systems.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research to explore new chemical spaces and reaction pathways.

Basic Information

Item	Detail
Product Name	[1,1'-Biphenyl]-4-Carboxylic Acid, 2,2',4'-Trifluoro-
CAS No.	1261950-00-8
Molecular Formula	C13H7F3O2
Molecular Weight	252.19 g/mol
Synonyms	2,2',4'-Trifluoro[1,1'-biphenyl]-4-carboxylic acid; 2,2',4'-Trifluorobiphenyl-4-carboxylic acid; 4-Carboxy-2,2',4'-trifluorobiphenyl; Biphenyl-4-carboxylic acid, 2,2',4'-trifluoro-; 2,2',4'-Trifluoro-4-biphenylcarboxylic acid
EINECS	Contact for details

Quality Control

Our [1,1'-Biphenyl]-4-Carboxylic Acid, 2,2',4'-Trifluoro- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.