Description

4-Fluoro-3-(4-Fluoro-3-Methylphenyl)Benzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique bifluoro-substituted aromatic structure, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated aromatic cores in electronic and optoelectronic materials.
• Organic Synthesis Reagent: Employed in Suzuki-Miyaura and other cross-coupling reactions to introduce complex fluorinated biphenyl motifs.
• Chemical Biology Probe Development: Utilized as a scaffold for creating fluorescent tags or molecular probes due to its stable aromatic system.

Basic Information

Product Name	4-Fluoro-3-(4-Fluoro-3-Methylphenyl)Benzoic Acid
CAS No.	1261949-48-7
Molecular Formula	C14H10F2O2
Molecular Weight	248.23 g/mol
Synonyms	4-Fluoro-3-(4-fluoro-3-methylphenyl)benzoic acid; 2-Fluoro-4'-(2-fluoro-5-methylphenyl)benzoic acid; 3-(4-Fluoro-3-methylphenyl)-4-fluorobenzoic acid; [1,1'-Biphenyl]-2-carboxylic acid, 4-fluoro-3'-fluoro-5-methyl-; 4-Fluoro-3-(4-fluoro-3-methylphenyl)benzoic acid CAS 1261949-48-7; 4-Fluoro-3-(4-fluoro-3-methyl-phenyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3-(4-Fluoro-3-Methylphenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.