Description

5-(2,5-Difluorophenyl)Picolinic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced chemical synthesis. This compound is valued for its unique molecular architecture, which incorporates both a picolinic acid moiety and a difluorophenyl group, enabling precise modifications in target molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Serves as a critical building block for developing new-generation herbicides and fungicides with enhanced efficacy and selectivity.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) in material science.
• Organic Electronics: Acts as a functional monomer or dopant in the research and development of organic semiconductors and light-emitting materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	5-(2,5-Difluorophenyl)Picolinic Acid
CAS No.	1261947-80-1
Molecular Formula	C12H7F2NO2
Molecular Weight	235.19 g/mol
Synonyms	5-(2,5-Difluorophenyl)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 5-(2,5-difluorophenyl)-; 2,5-Difluoro-5'-carboxy-2,3'-bipyridine (related structure); Picolinic acid, 5-(2,5-difluorophenyl)-; Difluorophenyl picolinic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(2,5-Difluorophenyl)Picolinic Acid is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure compliance with exacting purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.