Description

4-Fluoro-2'-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid is a high-purity biphenyl derivative featuring both a carboxylic acid and a phenolic hydroxyl group, making it a versatile and valuable synthetic intermediate. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its rigid biphenyl core.
• Chemical Biology Probes: Useful for designing fluorescent tags, photoaffinity labels, and other molecular probes for biological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized biphenyl scaffolds.

Basic Information

Product Name	4-Fluoro-2'-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid
CAS No.	1261943-94-5
Molecular Formula	C₁₃H₉FO₃
Molecular Weight	232.21 g/mol
Synonyms	3'-Fluoro-6-hydroxybiphenyl-2-carboxylic acid; 2'-Hydroxy-4-fluorobiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-2'-hydroxy-; 4-Fluoro-2'-hydroxybiphenyl-3-carboxylic acid; 3-Carboxy-4-fluoro-2'-hydroxybiphenyl
EINECS	Contact for details

Quality Control

Every batch of 4-Fluoro-2'-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.