Description

4-Fluoro-3'-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid is a high-purity biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a phenolic hydroxyl group on a fluorinated biphenyl scaffold, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Ligand Synthesis: Used for constructing sophisticated ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or functional unit in the development of specialty polymers and liquid crystals.
• Agrochemical Development: Intermediate for creating new-generation herbicides and fungicides with enhanced activity.
• Chemical Biology Probes: Building block for fluorescent tags and molecular probes used in diagnostic and imaging applications.
• Academic & Industrial R&D: Fundamental research chemical for exploring new synthetic methodologies and structure-activity relationships (SAR).

Basic Information

Product Name	4-Fluoro-3'-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid
CAS No.	1261938-23-1
Molecular Formula	C₁₃H₉FO₃
Molecular Weight	232.21 g/mol
Synonyms	3'-Hydroxy-4-fluoro-[1,1'-biphenyl]-3-carboxylic acid; 3-(3'-Hydroxy-4-fluorobiphenyl-3-yl)propanoic acid (related); 4-Fluoro-3'-hydroxybiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4-fluoro-3'-hydroxy-; Biphenyl-3-carboxylic acid derivative; Fluorinated biphenyl carboxylic acid; F-HO-Biphenyl-COOH; Research compound 1261938-23-1
EINECS	Contact for details

Quality Control

Our 4-Fluoro-3'-Hydroxy-[1,1'-Biphenyl]-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment. For long-term storage, consider using an inert atmosphere to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.