Description

3-(4-Acetylphenyl)-4-Fluorobenzoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound is valued for its bifunctional structure, featuring both a carboxylic acid and an acetyl group on a fluorinated biphenyl core, enabling precise molecular construction. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides where the fluorine atom and the biphenyl scaffold can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a sophisticated building block for creating fluorinated organic semiconductors, charge-transport materials, and liquid crystal compounds for electronic displays.
• Advanced Polymer Chemistry: Incorporated as a monomer or cross-linking agent to engineer specialty polymers with specific thermal, optical, or chemical resistance properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-(4-Acetylphenyl)-4-Fluorobenzoic Acid
CAS No.	1261938-14-0
Molecular Formula	C15H11FO3
Molecular Weight	258.25 g/mol
Synonyms	4'-Acetyl-4-fluoro[1,1'-biphenyl]-3-carboxylic acid; 3-(4-Acetylphenyl)-4-fluorobenzoic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4'-acetyl-4-fluoro-; 4-Fluoro-3-(4-acetylphenyl)benzoic acid; 4'-Acetyl-4-fluorobiphenyl-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Acetylphenyl)-4-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.