Description

5-(3-Chlorophenyl)-2-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both halogen and fluorine substituents to modulate the reactivity, lipophilicity, and metabolic stability of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning the properties of complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a carboxylic acid handle for amide bond formation in medicinal chemistry campaigns.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for exploring new synthetic methodologies and developing novel fluorinated compounds.

Basic Information

Product Name	5-(3-Chlorophenyl)-2-Fluorobenzoic Acid
CAS No.	1261933-47-4
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	2-Fluoro-5-(3-chlorophenyl)benzoic Acid; 3-Chloro-5'-fluorobiphenyl-2-carboxylic Acid; 5-(3-Chlorophenyl)-2-fluorobenzoic acid; [1,1'-Biphenyl]-2-carboxylic acid, 3-chloro-5'-fluoro-; 3-Chloro-5'-fluoro[1,1'-biphenyl]-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(3-Chlorophenyl)-2-Fluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.