Description

3-(3-Chlorophenyl)-5-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. Its value lies in its unique molecular scaffold, which combines halogenated aromatic rings to enable precise structural modifications in target molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated structure for enhanced bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a foundational monomer for synthesizing specialized fluorinated compounds used in electronic display technologies.
• Organic Ligand for Catalysis: Functions as a precursor for creating complex ligands used in transition metal-catalyzed cross-coupling reactions.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and creating custom fluorinated aromatic compounds.
• Polymer Modification: Acts as a monomer or additive to introduce specific fluorinated and chlorinated aromatic properties into polymer chains for enhanced performance.

Basic Information

Product Name	3-(3-Chlorophenyl)-5-Fluorobenzoic Acid
CAS No.	1261929-09-2
Molecular Formula	C13H8ClFO2
Molecular Weight	250.65 g/mol
Synonyms	5-Fluoro-3'-chlorobiphenyl-3-carboxylic Acid; 3-(3-Chlorophenyl)-5-fluorobenzoic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 5-fluoro-3'-chloro-; 3'-Chloro-5-fluorobiphenyl-3-carboxylic Acid; 3-Chloro-5-fluorobenzoic Acid Phenyl Ester (related); 5-Fluoro-3'-(chloro)[1,1'-biphenyl]-3-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 3-(3-Chlorophenyl)-5-Fluorobenzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept away from strong bases and oxidizing agents. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.