Description

4-(4-Cyanophenyl)-2-Fluorobenzoic Acid CAS NO 1261929-01-4 is a high-purity, multifunctional aromatic carboxylic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both cyano and fluoro substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides that require specific fluorinated aromatic cores.
• Liquid Crystal & OLED Materials: Serves as a monomer or intermediate for creating advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs), due to its polarizable aromatic system.
• Polymer Chemistry: Used in the production of specialty polymers, such as polyamides and polyesters, where the introduction of fluorine and cyano groups can modify thermal stability and solubility.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies, including Suzuki-Miyaura and other cross-coupling reactions.
• Material Science: Intermediate in the development of metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and other porous materials for catalysis and gas storage.

Basic Information

Product Name	4-(4-Cyanophenyl)-2-Fluorobenzoic Acid
CAS No.	1261929-01-4
Molecular Formula	C14H8FNO2
Molecular Weight	241.22 g/mol
Synonyms	2-Fluoro-4'-(cyanophenyl)benzoic Acid; 4-(4-Cyanophenyl)-2-fluorobenzoic Acid; 2-Fluoro-[1,1'-biphenyl]-4-carboxylic Acid, 4'-cyano-; [1,1'-Biphenyl]-4-carboxylic acid, 4'-cyano-2-fluoro-; 4'-Cyano-2-fluorobiphenyl-4-carboxylic Acid; 2-Fluoro-4'-(4-cyanophenyl)benzoic Acid; 4-Carboxy-3-fluorobiphenyl-4'-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-(4-Cyanophenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.