Description

5-Fluoro-3-(Thiophen-3-Yl)Benzoic Acid is a high-value fluorinated aromatic building block that combines a benzoic acid core with thiophene and fluorine substituents, creating a versatile scaffold for advanced synthesis. This compound is critical for research and development in pharmaceutical chemistry, where its unique structure enables the fine-tuning of molecular properties such as lipophilicity, metabolic stability, and binding affinity. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in oncology, CNS, and anti-inflammatory research.
• Agrochemical Development: Used to create novel active ingredients for crop protection products, leveraging the bioactivity of the thiophene and fluorine motifs.
• Material Science Research: Acts as a monomer or functionalization agent in the development of organic semiconductors, conductive polymers, and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	5-Fluoro-3-(Thiophen-3-Yl)Benzoic Acid
CAS No.	1261925-85-2
Molecular Formula	C11H7FO2S
Molecular Weight	222.24 g/mol
Synonyms	3-(3-Thienyl)-5-fluorobenzoic Acid; 5-Fluoro-3-(3-thienyl)benzoic Acid; 5-Fluoro-3-thiophen-3-ylbenzoic Acid; Benzoic acid, 5-fluoro-3-(3-thienyl)-; 1261925-85-2; 5-Fluoro-3-(thiophen-3-yl)benzoic acid; 5-Fluoro-3-(3-thiophenyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-(Thiophen-3-Yl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.