Description

6-Methyl-2-(2-Trifluoromethylphenyl)Benzoic Acid is a specialized fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethylphenyl group, makes it a valuable intermediate for creating compounds with enhanced biological activity and physicochemical properties. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring fluorinated motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance activity and environmental profile.
• Material Science Research: Serves as a precursor for specialty polymers and liquid crystals, contributing to unique optical and electronic properties.
• Chemical Research & Development: A versatile reagent for constructing complex organic molecules in academic and industrial R&D settings.
• Fluorinated Compound Library Synthesis: Essential for creating diverse screening libraries in medicinal chemistry for hit identification and lead optimization.

Basic Information

Product Name	6-Methyl-2-(2-Trifluoromethylphenyl)Benzoic Acid
CAS No.	1261888-13-4
Molecular Formula	C15H11F3O2
Molecular Weight	280.24 g/mol
Synonyms	2-(2-(Trifluoromethyl)phenyl)-6-methylbenzoic acid; 6-Methyl-2-[2-(trifluoromethyl)phenyl]benzoic acid; 2-Methyl-6-(2-trifluoromethylphenyl)benzoic acid; α,α,α-Trifluoro-2',6'-dimethyl-[1,1'-biphenyl]-2-carboxylic acid; Biphenyl-2-carboxylic acid, 2',6'-dimethyl-α,α,α-trifluoro-; 1261888-13-4; 6-Methyl-2-(2-trifluoromethyl-phenyl)-benzoic acid
EINECS	Contact for details

Quality Control

Our 6-Methyl-2-(2-Trifluoromethylphenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.