Description

2-Chloro-4-(3-Trifluoromethoxyphenyl)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid building block. Its unique structure, featuring both chloro and trifluoromethoxy substituents, makes it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging the bioactivity of the trifluoromethoxy group.
• Liquid Crystal & OLED Materials: Serves as a precursor for advanced electronic materials, where its aromatic core and halogenated groups contribute to desired electronic and morphological properties.
• Organic Synthesis & Chemical Research: A versatile reagent for coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and for introducing functionalized benzoic acid motifs into complex molecules.
• Polymer Modification: Can be used to synthesize specialized monomers for high-performance polymers with enhanced thermal stability and chemical resistance.

Basic Information

Product Name	2-Chloro-4-(3-Trifluoromethoxyphenyl)Benzoic Acid
CAS No.	1261855-01-9
Molecular Formula	C14H8ClF3O3
Molecular Weight	316.66 g/mol
Synonyms	2-Chloro-4-[3-(trifluoromethoxy)phenyl]benzoic acid; Benzoic acid, 2-chloro-4-[3-(trifluoromethoxy)phenyl]-; 4-(3-Trifluoromethoxyphenyl)-2-chlorobenzoic Acid; 2-Chloro-4-(3-trifluoromethoxy-phenyl)-benzoic acid; 1261855-01-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3-Trifluoromethoxyphenyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.