Description

2-Fluoro-4-(3-Trifluoromethoxyphenyl)Benzoic Acid is a high-value fluorinated aromatic building block with a distinct trifluoromethoxy substituent. This compound is critical for medicinal chemistry and advanced materials research, where its unique electronic and steric properties enable the fine-tuning of molecular interactions. It is primarily sought after by pharmaceutical R&D teams and agrochemical manufacturers for the synthesis of novel active ingredients and functional intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in CNS and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the stability of the trifluoromethoxy group.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in high-performance display technologies.
• Organic Electronics: Employed in the synthesis of electron-transport materials and semiconductors for OLEDs and OFETs.
• Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create complex biaryl structures.
• Fluorine Chemistry Studies: Used as a model compound to study the influence of fluorine and trifluoromethoxy groups on acidity and reactivity.

Basic Information

Product Name	2-Fluoro-4-(3-Trifluoromethoxyphenyl)Benzoic Acid
CAS No.	1261837-34-6
Molecular Formula	C14H8F4O3
Molecular Weight	300.21 g/mol
Synonyms	2-Fluoro-4-[3-(trifluoromethoxy)phenyl]benzoic acid; 4-(3-Trifluoromethoxyphenyl)-2-fluorobenzoic Acid; Benzoic acid, 2-fluoro-4-[3-(trifluoromethoxy)phenyl]-; 1261837-34-6; 2-Fluoro-4-(3-trifluoromethoxyphenyl)benzoic acid; 2-Fluoro-4-(α,α,α-trifluoro-m-tolyloxy)benzoic Acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(3-Trifluoromethoxyphenyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.