Description

3-[3-Fluoro-5-(Trifluoromethoxy)Phenyl]Propionicacid is a high-value fluorinated aromatic building block, specifically a phenylpropionic acid derivative, with the CAS registry number 1261828-37-8. This compound is critical for introducing specific fluorine-containing motifs into target molecules, enabling the fine-tuning of their physicochemical and biological properties. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy and fluorine groups enhance bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving performance characteristics.
• Advanced Polymer Modification: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and surface properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new fluorination chemistry and building complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Item	Detail
Product Name	3-[3-Fluoro-5-(Trifluoromethoxy)Phenyl]Propionic Acid
CAS No.	1261828-37-8
Molecular Formula	C10H6F4O3
Molecular Weight	250.15 g/mol
Synonyms	3-(3-Fluoro-5-(trifluoromethoxy)phenyl)propanoic acid; 3-(3-Fluoro-5-(trifluoromethoxy)phenyl)propionic acid; 1261828-37-8; 3-Fluoro-5-(trifluoromethoxy)benzenepropanoic acid; β-(3-Fluoro-5-(trifluoromethoxy)phenyl)propionic acid; 3-(3-Fluoro-5-trifluoromethoxy-phenyl)-propionic acid
EINECS	Contact for details

Quality Control

Every batch of 3-[3-Fluoro-5-(Trifluoromethoxy)Phenyl]Propionic Acid is manufactured and tested under strict quality management protocols. We ensure the product meets high-purity standards suitable for research and industrial synthesis. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.