Description

5-Fluoro-3-(4-Trifluoromethylphenyl)Benzoic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethyl and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of specialty materials and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in oncology, CNS, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity.
• Liquid Crystal Materials: Serves as a core component or side-chain modifier in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in OLED devices.
• Specialty Polymer Modification: Incorporated into polymer chains to impart specific chemical resistance, thermal stability, or surface properties.
• Chemical Research & Development: A versatile reagent for exploring new fluorination chemistry and constructing complex aromatic systems in academic and industrial labs.

Basic Information

Product Name	5-Fluoro-3-(4-Trifluoromethylphenyl)Benzoic Acid
CAS No.	1261824-93-4
Molecular Formula	C14H8F4O2
Molecular Weight	284.21 g/mol
Synonyms	3-(4-(Trifluoromethyl)phenyl)-5-fluorobenzoic acid; 5-Fluoro-3-[4-(trifluoromethyl)phenyl]benzoic acid; Benzoic acid, 5-fluoro-3-[4-(trifluoromethyl)phenyl]-; 5-Fluoro-3-(4-trifluoromethylphenyl)benzoic acid; 5-Fluoro-3-(alpha,alpha,α-trifluoro-p-tolyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3-(4-Trifluoromethylphenyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.