Description

Methyl 2,5-Difluoro-4-Hydroxybenzoate is a high-purity fluorinated aromatic ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the strategic placement of fluorine atoms and functional groups, enabling precise molecular modifications for performance-driven applications. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where fluorine incorporation enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers and components in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, improving material properties such as chemical resistance, thermal stability, and surface characteristics.
• Chemical Research & Development: A versatile scaffold in medicinal and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.

Basic Information

Product Name	Methyl 2,5-Difluoro-4-Hydroxybenzoate
CAS No.	1261684-74-5
Molecular Formula	C8H6F2O3
Molecular Weight	188.13 g/mol
Synonyms	Methyl 4-Hydroxy-2,5-difluorobenzoate; 2,5-Difluoro-4-hydroxybenzoic Acid Methyl Ester; Benzoic acid, 2,5-difluoro-4-hydroxy-, methyl ester; Methyl 2,5-difluoro-4-hydroxybenzoate; 4-Hydroxy-2,5-difluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2,5-Difluoro-4-Hydroxybenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.