Description

Methyl 3-Cyano-2-Fluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its unique molecular structure, featuring both cyano and fluoro substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances bioavailability and metabolic stability.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and liquid crystals, leveraging its aromatic and polar functional groups.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create diverse biaryl structures.
• Fluorine Chemistry Studies: Used in academic and industrial labs to study the effects of fluorine substitution on reaction pathways and molecular properties.

Basic Information

Product Name	Methyl 3-Cyano-2-Fluorobenzoate
CAS No.	1261453-50-2
Molecular Formula	C9H6FNO2
Molecular Weight	179.15 g/mol
Synonyms	2-Fluoro-3-cyanobenzoic acid methyl ester; Methyl 2-fluoro-3-cyanobenzoate; Benzoic acid, 3-cyano-2-fluoro-, methyl ester; 3-Cyano-2-fluorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Cyano-2-Fluorobenzoate adheres to stringent quality management protocols. Each batch is analyzed using advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. The compound may be hygroscopic; handle under dry conditions to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.