Description

2-Methyl-5-(Trifluoromethoxy)Benzoyl Chloride, 97% is a high-purity, reactive aromatic acid chloride derivative, distinguished by the presence of a trifluoromethoxy substituent. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for synthesizing complex molecules. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the 2-methyl-5-(trifluoromethoxy)benzoyl moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or modifying agent for introducing aromatic ester and amide linkages into high-performance polymers.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and other functional materials.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Methyl-5-(Trifluoromethoxy)Benzoyl Chloride, 97%
CAS No.	1261445-13-9
Molecular Formula	C9H6ClF3O2
Molecular Weight	238.59 g/mol
Synonyms	2-Methyl-5-(trifluoromethoxy)benzoyl chloride; 5-(Trifluoromethoxy)-2-methylbenzoyl chloride; α,α,α-Trifluoro-o-cresyl-5-carbonyl chloride; 2-Methyl-5-(trifluoromethoxy)benzoic acid chloride; m-Trifluoromethoxy-o-toluoyl chloride; Benzoyl chloride, 2-methyl-5-(trifluoromethoxy)-; CAS 1261445-13-9
EINECS	Contact for details

Quality Control

Our 2-Methyl-5-(Trifluoromethoxy)Benzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure the 97% minimum purity and consistent impurity profile. Certificates of Analysis (COA) with full traceability are provided for each lot, supporting development and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, alcohols, and strong bases. Keep under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain purity and reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.