Description

4,5-Difluoro-2-methoxybenzoic acid methyl ester is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, especially those requiring difluoromethoxybenzene motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides with enhanced activity and selectivity.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens in display technology applications.
• Organic Electronic Materials: Building block for electron-transport materials and semiconductors in OLEDs and OFETs.
• Chemical Research: Versatile starting material for Suzuki-Miyaura and other cross-coupling reactions to create diverse compound libraries.
• Fluorinated Ligand Synthesis: Used to prepare specialized ligands for catalysis and material science.

Basic Information

Product Name	4,5-Difluoro-2-methoxybenzoic Acid Methyl Ester
CAS No.	1261444-15-8
Molecular Formula	C10H8F2O3
Molecular Weight	214.16 g/mol
Synonyms	Methyl 4,5-difluoro-2-methoxybenzoate; 2-Methoxy-4,5-difluorobenzoic acid methyl ester; Benzoic acid, 4,5-difluoro-2-methoxy-, methyl ester; 4,5-Difluoro-2-methoxy-benzoic acid methyl ester; Methyl 4,5-difluoro-2-methoxybenzoate; 1261444-15-8
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-methoxybenzoic acid methyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.