Description

1-(2-(Trifluoromethyl)Phenyl)-1H-Pyrazole-4-Carboxylic Acid is a high-value trifluoromethylated pyrazole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a pyrazole heterocycle with a trifluoromethylphenyl group, enabling the fine-tuning of physicochemical properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis, facilitating challenging chemical transformations.
• Material Science Research: Employed in the development of advanced organic electronic materials, such as OLEDs and semiconductors, due to its electron-withdrawing characteristics.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Bioconjugation & Probe Chemistry: The carboxylic acid functional group allows for efficient conjugation to biomolecules, making it useful for creating diagnostic probes and biochemical tools.

Basic Information

Product Name	1-(2-(Trifluoromethyl)Phenyl)-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1260855-51-3
Molecular Formula	C11H7F3N2O2
Molecular Weight	256.18 g/mol
Synonyms	1-[2-(Trifluoromethyl)phenyl]-1H-pyrazole-4-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 1-[2-(trifluoromethyl)phenyl]-; 2-(Trifluoromethyl)phenylpyrazole-4-carboxylic acid; α,α,α-Trifluoro-o-tolyl pyrazole-4-carboxylic acid; 1-(2-Trifluoromethylphenyl)pyrazole-4-carboxylic acid; 1-(o-Trifluoromethylphenyl)-1H-pyrazole-4-carboxylic acid; TFMP-Pz-COOH
EINECS	Contact for details

Quality Control

Our 1-(2-(Trifluoromethyl)Phenyl)-1H-Pyrazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and full characterization data are provided with every shipment. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.