Description

1-(2,4-Difluorophenyl)Cyclopentane-1-Carboxylic Acid is a high-purity fluorinated organic building block of significant commercial interest. This compound serves as a critical intermediate in the synthesis of advanced pharmaceutical active ingredients and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the difluorophenyl moiety can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with unique electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.
• Academic and Industrial R&D: A valuable reagent for exploratory chemistry in fluorination strategies and carbocyclic acid chemistry.

Basic Information

Product Name	1-(2,4-Difluorophenyl)Cyclopentane-1-Carboxylic Acid
CAS No.	1260784-54-0
Molecular Formula	C₁₂H₁₂F₂O₂
Molecular Weight	226.22 g/mol
Synonyms	1-(2,4-Difluorophenyl)cyclopentanecarboxylic acid; 2,4-Difluoro-α-(cyclopentylidene)benzenacetic acid; Cyclopentanecarboxylic acid, 1-(2,4-difluorophenyl)-; 1-(2,4-Difluorophenyl)cyclopentane-1-carboxylic acid; 1260784-54-0; 1-(2,4-Difluorophenyl)-1-cyclopentanecarboxylic acid; α-(2,4-Difluorophenyl)cyclopentanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorophenyl)Cyclopentane-1-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.