Description

5-Fluoro-2-(Methylthio)Benzoic Acid is a high-value fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and a methylthio substituent, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in kinase inhibitor and anti-inflammatory research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the fluorine atom improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Building block for synthesizing fluorinated liquid crystals, polymers, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in fluorination and cross-coupling reactions.

Basic Information

Product Name	5-Fluoro-2-(Methylthio)Benzoic Acid
CAS No.	1256727-01-1
Molecular Formula	C8H7FO2S
Molecular Weight	186.20 g/mol
Synonyms	2-(Methylthio)-5-fluorobenzoic Acid; 5-Fluoro-2-(methylsulfanyl)benzoic Acid; Benzoic acid, 5-fluoro-2-(methylthio)-; 5-Fluoro-2-methylthiobenzoic Acid; 5-F-2-MTBA; 1256727-01-1; 5-Fluoro-2-(methylmercapto)benzoic Acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Methylthio)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards. Specifications can be tailored to meet specific project requirements, including custom purity grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.