Description

Dimethyl 2-Bromo-5-Fluoroterephthalic Acid is a high-purity, multi-functional aromatic building block essential for advanced organic synthesis. This compound is valued for its precise molecular architecture, which enables the controlled introduction of bromo and fluoro substituents into complex target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting specific biological receptors where halogenated aromatic rings are critical for potency and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine and bromine atoms can enhance bioactivity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the development of novel organic electronic materials, such as semiconductors for OLEDs or OFETs, where halogenated terephthalate derivatives can tune electronic properties.
• Custom Chemical Synthesis: A versatile scaffold for contract research organizations (CROs) and custom synthesis houses building bespoke molecules for client projects.
• Fluorescent Probe and Dye Chemistry: Acts as a core component in the synthesis of advanced fluorescent tags and dyes used in bioimaging and diagnostics.

Basic Information

Product Name	Dimethyl 2-Bromo-5-Fluoroterephthalic Acid
CAS No.	1245807-10-6
Molecular Formula	C10H8BrFO4
Molecular Weight	291.07 g/mol
Synonyms	Dimethyl 2-bromo-5-fluorobenzene-1,4-dicarboxylate; 2-Bromo-5-fluoroterephthalic acid dimethyl ester; 1,4-Benzenedicarboxylic acid, 2-bromo-5-fluoro-, dimethyl ester; Methyl 2-bromo-5-fluoroterephthalate; Dimethyl bromofluoroterephthalate
EINECS	Contact for details

Quality Control

Every batch of Dimethyl 2-Bromo-5-Fluoroterephthalic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.