Description

(±)-Pramipexole CAS NO 1244656-98-1 is a high-purity chemical compound primarily used as a key intermediate in pharmaceutical research and development. This compound is of significant commercial interest for its role in the synthesis of active pharmaceutical ingredients (APIs), particularly in the field of neurology. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic laboratories engaged in the development of therapeutic agents targeting neurological disorders.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of Pramipexole dihydrochloride, the active ingredient used in medications for Parkinson's disease and Restless Legs Syndrome (RLS).
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Research & Development: Used in preclinical and clinical research to study dopaminergic pathways, receptor activity, and the development of novel neurological therapies.
• Process Chemistry: Employed in route scouting, optimization, and scale-up studies for the efficient and cost-effective manufacturing of related APIs.
• Impurity Profiling: Utilized as a marker or starting material for the synthesis and identification of potential process-related impurities and degradants.

Basic Information

Product Name	(±)-Pramipexole
CAS No.	1244656-98-1
Molecular Formula	C10H17N3S
Molecular Weight	203.33 g/mol
Synonyms	(±)-Pramipexole; Pramipexole Racemate; (RS)-Pramipexole; 6-Propylamino-4,5,6,7-tetrahydro-1,3-benzothiazole-2-amine; SND 919; SND-919; U-98,528; U-98528
EINECS	Contact for details

Quality Control

Our (±)-Pramipexole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and composition, suitable for pharmaceutical R&D applications. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.