Description

3-Bromo-4,5-Difluorobenzoic Acid is a high-purity, multi-functional aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of halogen and fluorine substituents on the benzoic acid core, which allows for precise structural modifications and the introduction of unique physicochemical properties into target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by material scientists developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors, anti-cancer agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Serves as a versatile precursor in the design and synthesis of new-generation herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Used in the synthesis of fluorinated aromatic components for advanced electronic displays and organic light-emitting diodes (OLEDs), contributing to improved performance and durability.
• Polymer Modification: Acts as a monomer or cross-linking agent for engineering high-performance polymers with enhanced thermal stability, chemical resistance, and specific surface properties.
• Chemical Research & Development: An essential reagent in academic and industrial R&D labs for exploring novel organic reactions, catalytic processes, and structure-activity relationships (SAR).
• Fluorine Chemistry Building Block: Provides a defined aromatic scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), enabling the construction of complex, fluorinated molecular architectures.

Basic Information

Item	Details
Product Name	3-Bromo-4,5-Difluorobenzoic Acid
CAS No.	1244642-73-6
Molecular Formula	C7H3BrF2O2
Molecular Weight	237.00 g/mol
Synonyms	3-Bromo-4,5-difluorobenzoic acid; Benzoic acid, 3-bromo-4,5-difluoro-; 4,5-Difluoro-3-bromobenzoic acid; 3-Br-4,5-F2-BA; 3-Bromo-4,5-difluorobenzenecarboxylic acid; 1244642-73-6; 3-Bromo-4,5-difluoro-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-4,5-Difluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.