Description

3-(2-Oxopyrrolidin-1-Yl)-5-(Trifluoromethyl)Benzoic Acid is a high-value, multifunctional organic building block characterized by its benzoic acid core substituted with a pyrrolidinone and a trifluoromethyl group. This compound is critical for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals due to its unique structural features. It is primarily sought after by pharmaceutical R&D teams, agrochemical manufacturers, and specialty chemical producers for creating compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group contributes to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for designing novel ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects in CDMO (Contract Development and Manufacturing Organization) settings.

Basic Information

Product Name	3-(2-Oxopyrrolidin-1-Yl)-5-(Trifluoromethyl)Benzoic Acid
CAS No.	1244030-93-0
Molecular Formula	C13H10F3NO3
Molecular Weight	285.22 g/mol
Synonyms	5-(Trifluoromethyl)-3-(2-oxo-1-pyrrolidinyl)benzoic Acid; 3-(2-Oxo-1-pyrrolidinyl)-5-(trifluoromethyl)benzoic Acid; 1-[3-Carboxy-5-(trifluoromethyl)phenyl]-2-pyrrolidinone; 3-(2-Oxopyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid; Benzoic acid, 3-(2-oxo-1-pyrrolidinyl)-5-(trifluoromethyl)-; 1244030-93-0
EINECS	Contact for details

Quality Control

Our 3-(2-Oxopyrrolidin-1-Yl)-5-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in regulated environments, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.