Description

2-Chloro-4,6-Difluorobenzoic Acid is a high-purity, multi-functional benzoic acid derivative distinguished by its specific halogen substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the biological activity of the difluoro-chloro benzoate core.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Chemistry Modifier: Acts as a monomer or functionalization agent to introduce specific halogenated aromatic groups into polymer chains, altering material properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a carboxylate precursor in medicinal chemistry and material science research.
• Chemical Research & Development: Essential for academic and industrial R&D focused on fluorochemistry and the exploration of new chemical entities.

Basic Information

Item	Detail
Product Name	2-Chloro-4,6-Difluorobenzoic Acid
CAS No.	1242339-67-8
Molecular Formula	C7H3ClF2O2
Molecular Weight	192.55 g/mol
Synonyms	2-Chloro-4,6-difluorobenzoic acid; Benzoic acid, 2-chloro-4,6-difluoro-; 4,6-Difluoro-2-chlorobenzoic acid; 2-Chloro-4,6-difluorobenzoate; 1242339-67-8; 2-Cl-4,6-F2-BA
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-4,6-Difluorobenzoic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established specifications using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We operate under a cGMP-compliant quality management system to meet the rigorous demands of pharmaceutical and advanced material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.