Description

3-Fluoro-5-(Pentafluorosulfur)Cinnamic Acid is a high-value fluorinated organic building block characterized by its unique combination of a cinnamic acid backbone with fluorine and pentafluorosulfur substituents. This compound matters for its role in facilitating the synthesis of advanced materials and pharmaceuticals, where its specific fluorination pattern can dramatically alter molecular properties like bioavailability, metabolic stability, and lipophilicity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for creating novel compounds with targeted functionalities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, where the fluorine and sulfur groups can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials, contributing to improved performance and durability.
• Polymer Modification: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, or specific optical characteristics.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes due to its distinct spectroscopic signature.
• Cross-Coupling Reactions: Functions as a sophisticated reactant in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to construct complex biaryl systems.

Basic Information

Product Name	3-Fluoro-5-(Pentafluorosulfur)Cinnamic Acid
CAS No.	1240261-82-8
Molecular Formula	C9H4F6O2S
Molecular Weight	290.19 g/mol
Synonyms	(E)-3-[3-Fluoro-5-(pentafluoro-λ6-sulfanyl)phenyl]acrylic acid; 3-Fluoro-5-(pentafluorosulfanyl)cinnamic acid; 3-Fluoro-5-(SF5)cinnamic acid; (E)-3-(3-Fluoro-5-(pentafluorosulfanyl)phenyl)-2-propenoic acid; 2-Propenoic acid, 3-[3-fluoro-5-(pentafluoro-λ6-sulfanyl)phenyl]-, (2E)-; SF5-Cinnamic Acid Derivative
EINECS	Contact for details

Quality Control

Our 3-Fluoro-5-(Pentafluorosulfur)Cinnamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.