Description

3-Chloro-5-(Pentafluorosulfur)Cinnamic Acid is a specialized fluorinated cinnamic acid derivative that serves as a high-value synthetic intermediate. Its unique structure, featuring both chloro and pentafluorosulfur substituents, makes it a critical building block for introducing specific functional groups and enhancing molecular properties. This compound is primarily sought by research and development teams in the pharmaceutical and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammation.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the pentafluorosulfur group can improve bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated organic semiconductors and liquid crystal molecules in display technologies.
• Polymer Modification: Incorporated into polymer backbones to impart specific characteristics like chemical resistance, thermal stability, or unique optical properties.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions for constructing complex biaryl systems.
• Fluorine Chemistry Research: Essential reagent for studying the effects of the SF5 (pentafluorosulfur) group, a "super-trifluoromethyl" group, in organic synthesis.

Basic Information

Product Name	3-Chloro-5-(Pentafluorosulfur)Cinnamic Acid
CAS No.	1240261-79-3
Molecular Formula	C9H4ClF5O2S
Molecular Weight	306.64 g/mol
Synonyms	(E)-3-(3-Chloro-5-(pentafluoro-λ6-sulfanyl)phenyl)acrylic acid; 3-Chloro-5-(SF5)cinnamic acid; 3-Chloro-5-pentafluorosulfanylcinnamic acid; (2E)-3-[3-Chloro-5-(pentafluoro-λ6-sulfanyl)phenyl]prop-2-enoic acid; 3-Chloro-5-(SF5)-trans-cinnamic acid; 3-Chloro-5-(pentafluorosulfur)benzenepropenoic acid; 1240261-79-3
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(Pentafluorosulfur)Cinnamic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.