Description

Dimesna is a specialized organosulfur compound with significant utility in pharmaceutical and biochemical research. This compound matters for its role as a key intermediate and active pharmaceutical ingredient (API) in the development of cytoprotective agents and detoxification therapies. Industries that need it include pharmaceutical manufacturers, biotechnology research facilities, and advanced chemical synthesis laboratories developing novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of mesna and other thiol-based cytoprotective drugs used in chemotherapy.
• Biochemical Research: Utilized in studies involving sulfhydryl chemistry, redox biology, and the modulation of cellular glutathione pathways.
• Detoxification Agent Precursor: Acts as a prodrug or metabolite in the development of agents designed to protect against the toxic effects of certain chemotherapeutic drugs, such as ifosfamide and cyclophosphamide.
• Analytical Reference Standard: Employed as a high-purity standard in quality control (QC) and analytical method development within pharmaceutical quality assurance laboratories.
• Chemical Synthesis: Used in organic synthesis for introducing disulfide or thiol functionalities into more complex molecular architectures.

Basic Information

Product Name	Dimesna
CAS No.	1233389-51-9
Molecular Formula	C4H8Na2O6S2
Molecular Weight	270.20 g/mol
Synonyms	Disodium 2,2'-dithiobis(ethanesulfonate); BNPT; Dimesna disodium; Mesna disulfide disodium salt; Sodium 2,2'-dithiodiethanesulfonate; Uromitexan disulfide; NSC 113891; 2,2'-Dithiobis(ethanesulfonic acid) disodium salt
EINECS	Contact for details

Quality Control

Our Dimesna is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC for assay and related substances, to meet stringent specifications suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.