Description

8-Fluorochroman-3-Carboxylic Acid CAS NO 1229042-30-1 is a high-purity fluorinated chroman derivative, a key chiral building block in modern organic synthesis. Its value lies in its unique molecular scaffold, which incorporates both a fluorine atom and a carboxylic acid functional group, enabling precise structural modifications for advanced material and pharmaceutical research. This compound is essential for R&D chemists and process development scientists working in pharmaceutical intermediates, agrochemicals, and materials science, particularly for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas where fluorinated compounds are advantageous.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorochroman structure can contribute to improved biological activity and environmental profile.
• Ligand and Catalyst Development: Acts as a chiral scaffold or a functionalized starting material for constructing complex ligands used in asymmetric catalysis.
• Material Science Precursor: Employed in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors, where fluorine substitution tunes electronic properties.
• Chemical Biology Probe: Utilized as a building block for creating fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A valuable starting point for custom synthesis projects requiring specific fluorinated heterocyclic architectures.

Basic Information

Item	Detail
Product Name	8-Fluorochroman-3-Carboxylic Acid
CAS No.	1229042-30-1
Molecular Formula	C10H9FO3
Molecular Weight	196.18 g/mol
Synonyms	8-Fluoro-3,4-dihydro-2H-1-benzopyran-3-carboxylic acid; 8-Fluoro-3-chromancarboxylic acid; 8-Fluorochroman-3-carboxylic acid; 2H-1-Benzopyran-3-carboxylic acid, 8-fluoro-3,4-dihydro-; 1229042-30-1; 8-Fluoro-3,4-dihydro-2H-chromene-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Fluorochroman-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.