Description

Balovaptan is a selective, orally bioavailable vasopressin V1a receptor antagonist. This compound is of significant interest for its potential therapeutic applications in central nervous system disorders. It is primarily utilized by pharmaceutical research and development organizations, contract research organizations (CROs), and academic institutions engaged in neuroscience and drug discovery. Balovaptan CAS NO 1228088-30-9 represents a high-value research chemical for developing novel treatments.

Application

• Pharmaceutical R&D: Key intermediate or reference standard in the development of vasopressin receptor-targeted therapeutics.
• Neuroscience Research: Tool compound for investigating the role of the vasopressin V1a receptor in social behavior, stress response, and related neurological pathways.
• Preclinical Studies: Used in animal models to evaluate pharmacokinetics, pharmacodynamics, and efficacy for conditions like autism spectrum disorder (ASD).
• Analytical Method Development: Serves as a critical standard for developing and validating HPLC, LC-MS, or other analytical methods for quality control.
• Chemical Synthesis: Acts as a building block or target molecule for medicinal chemists exploring structural analogs.
• Biochemical Assays: Used in high-throughput screening (HTS) and in vitro binding assays to characterize receptor interaction and selectivity.

Basic Information

Product Name	Balovaptan
CAS No.	1228088-30-9
Molecular Formula	C₂₀H₂₅FN₄O₃
Molecular Weight	388.44 g/mol
Synonyms	RG7314; RO5285119; 4-[(5S)-5-[(Dimethylamino)methyl]-2-methoxy-1-oxo-2,3-dihydro-1H-inden-4-yl]-3-fluoro-N-(2-pyridinylmethyl)benzamide; Balovaptan (RG7314); RG-7314; RO-5285119
EINECS	Contact for details

Quality Control

Our Balovaptan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR, MS), purity determination by HPLC, and control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.