Description

6-Fluoro-2-(Trifluoromethyl)Nicotinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and fluorine substituents make it an essential intermediate for developing novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atoms improve metabolic stability and lipophilicity.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of specialty polymers and liquid crystals.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Compound Manufacturing: Serves as a foundational material for synthesizing other complex, multi-fluorinated organic molecules.

Basic Information

Product Name	6-Fluoro-2-(Trifluoromethyl)Nicotinic Acid
CAS No.	1227599-87-2
Molecular Formula	C7H3F4NO2
Molecular Weight	209.10 g/mol
Synonyms	2-(Trifluoromethyl)-6-fluoronicotinic acid; 6-Fluoro-2-(trifluoromethyl)pyridine-3-carboxylic acid; 3-Pyridinecarboxylic acid, 6-fluoro-2-(trifluoromethyl)-; 6-Fluoro-2-trifluoromethylnicotinic acid; F2TNA; 1227599-87-2
EINECS	Contact for details

Quality Control

Our production of 6-Fluoro-2-(Trifluoromethyl)Nicotinic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.