Description

5-Cyano-2-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its benzoic acid core, cyano electron-withdrawing group, and trifluoromethyl substituent. This unique molecular architecture makes it an essential intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where enhanced stability and specific electronic properties are required. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its electron-deficient aromatic system.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on introducing fluorine and trifluoromethyl groups into complex molecules.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	5-Cyano-2-(Trifluoromethyl)Benzoic Acid
CAS No.	1227507-92-7
Molecular Formula	C9H4F3NO2
Molecular Weight	215.13 g/mol
Synonyms	2-(Trifluoromethyl)-5-cyanobenzoic Acid; 5-Cyano-2-(trifluoromethyl)benzoic Acid; Benzoic acid, 5-cyano-2-(trifluoromethyl)-; 2-Trifluoromethyl-5-cyanobenzoic Acid; 5-Cyano-alpha,alpha,α-trifluoro-o-toluic Acid
EINECS	Contact for details

Quality Control

Our 5-Cyano-2-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.