Description

Methyl 5-Amino-2,3-Difluorobenzoate is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique difluoro-substituted benzoate structure, which serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Polymer Modification: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, weatherability, and surface properties.
• Organic Electronic Materials: Utilized in the research and development of organic semiconductors and electron-transport materials for OLEDs and photovoltaic cells.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on fluorine chemistry, medicinal chemistry, and material science.

Basic Information

Product Name	Methyl 5-Amino-2,3-Difluorobenzoate
CAS No.	1227269-02-4
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	5-Amino-2,3-difluorobenzoic acid methyl ester; Methyl 5-amino-2,3-difluorobenzoate; Benzoic acid, 5-amino-2,3-difluoro-, methyl ester; 2,3-Difluoro-5-aminobenzoic acid methyl ester; Methyl 2,3-difluoro-5-aminobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Amino-2,3-Difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.