Description

2-(2,6-Difluoro-4-Nitrophenyl)Propanoic Acid is a high-purity fluorinated aromatic compound serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and nitro functional groups, which are essential for modulating the biological activity and physicochemical properties of target molecules. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in protease inhibitor and kinase inhibitor research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluoro and nitro groups contribute to efficacy and environmental profile.
• Material Science Research: Acts as a monomer or precursor for specialty polymers and liquid crystals, leveraging its aromatic rigidity and fluorine content.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific complex molecules under cGMP conditions.

Basic Information

Product Name	2-(2,6-Difluoro-4-Nitrophenyl)Propanoic Acid
CAS No.	1226776-82-4
Molecular Formula	C9H7F2NO4
Molecular Weight	231.15 g/mol
Synonyms	2-(2,6-Difluoro-4-nitrophenyl)propionic acid; α-Methyl-2,6-difluoro-4-nitrobenzenepropanoic acid; 2,6-Difluoro-4-nitro-α-methylbenzenepropanoic acid; 2-(2,6-Difluoro-4-nitrophenyl)propanoic acid; 1226776-82-4; Propanoic acid, 2-(2,6-difluoro-4-nitrophenyl)-; Benzenepropanoic acid, 2,6-difluoro-4-nitro-α-methyl-
EINECS	Contact for details

Quality Control

Our 2-(2,6-Difluoro-4-Nitrophenyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment supports applications requiring research-grade to cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.