Description

2-Methyl-3-(4-Trifluoromethoxyphenyl)Benzoic Acid is a high-value, multi-functional aromatic carboxylic acid derivative, distinguished by its trifluoromethoxy-substituted phenyl ring. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry, prized for its ability to impart unique physicochemical properties to target molecules. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for synthesizing specialized organic compounds used in electronic displays and optoelectronic devices.
• Polymer Modification: Acts as a monomer or additive to introduce specific functional groups into polymer chains, modifying thermal and chemical resistance.
• Organic Synthesis & Catalysis: Employed as a versatile reagent in cross-coupling reactions and as a ligand precursor in catalytic systems.
• Academic & Industrial R&D: Essential for medicinal chemistry programs and material science research in universities and corporate laboratories.

Basic Information

Product Name	2-Methyl-3-(4-Trifluoromethoxyphenyl)Benzoic Acid
CAS No.	1221722-10-6
Molecular Formula	C16H11F3O3
Molecular Weight	308.25 g/mol
Synonyms	3-Methyl-2-[4-(trifluoromethoxy)phenyl]benzoic acid; 2-Methyl-3-[4-(trifluoromethoxy)phenyl]benzoic acid; Benzoic acid, 2-methyl-3-[4-(trifluoromethoxy)phenyl]-; 2-Methyl-3-(4-trifluoromethoxyphenyl)benzoic acid; 2-Methyl-3-(p-trifluoromethoxyphenyl)benzoic acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-3-(4-Trifluoromethoxyphenyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets precise customer specifications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring consistency and traceability for demanding pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.