Description

2'-Fluoro-3'-Methoxybiphenyl-3-Carboxylic Acid is a high-purity, fluorinated biphenyl carboxylic acid derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate). Its value lies in its unique molecular scaffold, which is essential for constructing complex active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, especially in oncology and CNS research.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs, leveraging its biphenyl core and functional groups for molecular diversification.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to optimize drug potency, selectivity, and pharmacokinetic properties.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Agrochemical Intermediate: Potential use in the research and development of advanced crop protection agents.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and liquid crystals due to its rigid biphenyl structure.

Basic Information

Item	Detail
Product Name	2'-Fluoro-3'-Methoxybiphenyl-3-Carboxylic Acid
CAS No.	1215206-35-1
Molecular Formula	C14H11FO3
Molecular Weight	246.24 g/mol
Synonyms	3'-Methoxy-2'-fluorobiphenyl-3-carboxylic acid; [1,1'-Biphenyl]-3-carboxylic acid, 2'-fluoro-3'-methoxy-; 2-Fluoro-3'-methoxybiphenyl-3-carboxylic acid; 3-(2-Fluoro-3-methoxyphenyl)benzoic acid; 2'-Fluoro-3'-methoxy-[1,1'-biphenyl]-3-carboxylic acid; 2-Fluoro-3-methoxybiphenyl-3-carboxylic acid; Biphenyl-3-carboxylic acid, 2'-fluoro-3'-methoxy- derivative
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-3'-Methoxybiphenyl-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.