Description

3'-(Trifluoromethoxy)Biphenyl-3-Carboxylic Acid is a high-purity, multifunctional aromatic carboxylic acid derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the unique combination of the biphenyl scaffold and the trifluoromethoxy group, which imparts enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules in drug discovery and crop protection agent synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for the synthesis of specialized organic electronic materials, contributing to the molecular core of liquid crystals and emissive layers in OLED displays.
• Organic Synthesis & Catalysis: Acts as a versatile carboxylic acid component in coupling reactions (e.g., Suzuki, amidation) and as a ligand precursor in organometallic catalysis.
• Material Science Research: Employed in the development of novel polymers, metal-organic frameworks (MOFs), and other functional materials requiring rigid, fluorinated aromatic linkers.

Basic Information

Product Name	3'-(Trifluoromethoxy)Biphenyl-3-Carboxylic Acid
CAS No.	1215206-30-6
Molecular Formula	C14H9F3O3
Molecular Weight	282.22 g/mol
Synonyms	[3'-(Trifluoromethoxy)[1,1'-biphenyl]-3-yl]carboxylic acid; 3'-(Trifluoromethoxy)-[1,1'-biphenyl]-3-carboxylic acid; 3-Biphenyl-3'-carboxylic acid, 3'-(trifluoromethoxy)-; 3-Carboxy-3'-(trifluoromethoxy)biphenyl; Biphenyl-3-carboxylic acid, 3'-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 3'-(Trifluoromethoxy)Biphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. The container must be kept tightly sealed due to potential sensitivity to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.