Description

4,4'-Difluorobiphenyl-2,2'-Dicarboxylic Acid is a high-purity, functionalized biphenyl derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key precursor in the development of high-performance materials and active pharmaceutical ingredients (APIs), where its difluoro and dicarboxylic acid groups enable precise molecular engineering. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors for creating novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Liquid Crystal & OLED Material Synthesis: Serves as a core building block for creating novel organic semiconductors, liquid crystal display (LCD) components, and light-emitting materials for organic light-emitting diodes (OLEDs).
• High-Performance Polymer Monomer: Used in the production of specialty polyamides, polyesters, and polyimides that require enhanced thermal stability, chemical resistance, and specific optical properties.
• Agrochemical Active Ingredient Development: Employed in research and development for novel herbicides, fungicides, and plant growth regulators.
• Metal-Organic Framework (MOF) Construction: Acts as an organic linker in the design and synthesis of porous coordination polymers for gas storage, separation, and catalysis.
• Cross-Coupling Reaction Substrate: A valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.

Basic Information

Product Name	4,4'-Difluorobiphenyl-2,2'-Dicarboxylic Acid
CAS No.	1215205-82-5
Molecular Formula	C₁₄H₈F₂O₄
Molecular Weight	278.21 g/mol
Synonyms	2,2'-Biphenyldicarboxylic acid, 4,4'-difluoro-; 4,4'-Difluoro[1,1'-biphenyl]-2,2'-dicarboxylic acid; 4,4'-Difluoro-2,2'-biphenyldicarboxylic Acid; 4,4'-Difluorobiphenyl-2,2'-dicarboxylate; 4,4'-Difluoro-2,2'-dicarboxybiphenyl; DFBDA; 4,4'-DFBDA; 4,4'-Difluoro-2,2'-bibenzoic acid
EINECS	Contact for details

Quality Control

Our 4,4'-Difluorobiphenyl-2,2'-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect the hygroscopic and light-sensitive material from moisture and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.