Description

Ethyl 2-Fluoro-5-Hydroxybenzoate is a high-purity fluorinated benzoate ester, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a phenolic hydroxyl group, provides valuable reactivity for constructing complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a fluorinated component in the production of advanced liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with enhanced thermal and chemical resistance.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and etherifications to introduce fluorinated aromatic systems.
• Chemical Research & Development: A valuable tool for medicinal chemistry and material science research programs exploring structure-activity relationships.

Basic Information

Product Name	Ethyl 2-Fluoro-5-Hydroxybenzoate
CAS No.	1214387-36-6
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	2-Fluoro-5-hydroxybenzoic Acid Ethyl Ester; Ethyl 2-Fluoro-5-hydroxybenzoate; Benzoic acid, 2-fluoro-5-hydroxy-, ethyl ester; 5-Hydroxy-2-fluorobenzoic Acid Ethyl Ester; Ethyl 5-Hydroxy-2-fluorobenzoate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-Fluoro-5-Hydroxybenzoate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is supplied with each shipment to guarantee reproducible results in your application.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.