Description

Methyl 3-Fluoro-5-Methoxybenzoate is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its value lies in its dual functionalization, providing a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working on novel active ingredients, particularly in the areas of medicinal chemistry and crop protection.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Chemistry Modifier: Incorporated into polymer backbones to alter physical properties such as thermal stability, solubility, and refractive index for specialty plastics and coatings.
• Chemical Biology Probe Development: Utilized to create fluorinated analogs of bioactive molecules for studying metabolic pathways and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	Methyl 3-Fluoro-5-Methoxybenzoate
CAS No.	1214387-14-0
Molecular Formula	C9H9FO3
Molecular Weight	184.16 g/mol
Synonyms	3-Fluoro-5-methoxybenzoic acid methyl ester; Methyl 3-fluoro-5-methoxybenzoate; Benzoic acid, 3-fluoro-5-methoxy-, methyl ester; 5-Methoxy-3-fluorobenzoic acid methyl ester; 3-Fluoro-5-methoxymethyl benzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Fluoro-5-Methoxybenzoate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our standard grades comply with in-house specifications tailored for synthetic applications, and custom purity grades (e.g., >98%, >99%) can be supplied upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.