Description

Ethyl 4,5-Difluoro-2-Nitrobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial R&D departments for constructing novel active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the difluoro and nitro groups contribute to biological activity and metabolic stability.
• Material Science: Serves as a building block for advanced polymers and liquid crystals, leveraging its aromatic and fluorinated structure.
• Organic Synthesis: Employed in cross-coupling reactions and nucleophilic aromatic substitution to introduce functionalized benzoate motifs.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethyl 4,5-Difluoro-2-Nitrobenzoate
CAS No.	1214387-06-0
Molecular Formula	C9H7F2NO4
Molecular Weight	231.15 g/mol
Synonyms	Benzoic acid, 4,5-difluoro-2-nitro-, ethyl ester; Ethyl 4,5-difluoro-2-nitrobenzoate; 2-Nitro-4,5-difluorobenzoic acid ethyl ester; 4,5-Difluoro-2-nitrobenzoic acid ethyl ester; Ethyl 2-nitro-4,5-difluorobenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 4,5-Difluoro-2-Nitrobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.