Description

5-(2-Fluorophenyl)-2-Fluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique bifluorinated aromatic structure, which is essential for modulating the physicochemical properties of target molecules, particularly in pharmaceutical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides and pesticides, where the fluorinated phenyl group can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic cores in electronic materials, improving charge transport and thermal stability.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Polymer Modification: Acts as a monomer or cross-linking agent to introduce fluorine into polymer backbones, altering surface properties and chemical resistance.
• Academic & Contract Research: A valuable reagent for methodological studies in cross-coupling reactions and fluorination chemistry within academic and CRO settings.

Basic Information

Product Name	5-(2-Fluorophenyl)-2-Fluorobenzoic Acid
CAS No.	1214386-81-8
Molecular Formula	C13H8F2O2
Molecular Weight	234.20 g/mol
Synonyms	2'-Fluoro-[1,1'-biphenyl]-2-carboxylic acid, 2-Fluorinated; 2-Fluoro-5-(2-fluorophenyl)benzoic Acid; 5-(2-Fluorophenyl)-2-fluorobenzoic Acid; [1,1'-Biphenyl]-2-carboxylic acid, 2'-fluoro-; Biphenyl-2-carboxylic acid, 2'-fluoro- derivative; FC-1214386
EINECS	Contact for details

Quality Control

Our 5-(2-Fluorophenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.