Description

Methyl 2-Bromo-3-(Trifluoromethyl)Benzoate is a high-value, multi-functional aromatic ester building block designed for advanced organic synthesis. Its unique structure, featuring both bromo and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring trifluoromethylated aromatic cores.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Acts as a monomer or building block for creating specialty polymers and organic electronic materials.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Fluorine Chemistry Studies: A valuable compound for research into the effects of fluorine substitution on chemical reactivity and physical properties.

Basic Information

Product Name	Methyl 2-Bromo-3-(Trifluoromethyl)Benzoate
CAS No.	1214362-28-3
Molecular Formula	C9H6BrF3O2
Molecular Weight	283.04 g/mol
Synonyms	2-Bromo-3-(trifluoromethyl)benzoic acid methyl ester; Methyl 2-bromo-α,α,α-trifluoro-m-toluate; Benzoic acid, 2-bromo-3-(trifluoromethyl)-, methyl ester; Methyl 2-bromo-3-trifluoromethylbenzoate; 2-Bromo-3-trifluoromethylbenzoic acid methyl ester; m-Toluic acid, 2-bromo-α,α,α-trifluoro-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-3-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.